html, body {
	background-color: white;
}
body {
  background-repeat: no-repeat !important;
	background-attachment: fixed !important;
	background-position: center 50% !important;
	background-size: 50% !important;
}
body[data-release="alpha"] {
	background-image: url('/images/bnf-alpha-watermark.png') !important;
}
body[data-release="beta"] {
	background-image: url('/images/bnf-beta-watermark.png') !important;
}
/*a:visited,*/
/*a.visited {
	color: purple;
}*/
section.target-section {
	padding: 10px;
	border-radius: 0px;
	background-color: #eee;
	margin-bottom: 14px;
}

section.niceDecision,
section.smcDecision,
section.awmsgDecisions {
	margin-bottom: 50px;
}

section.niceDecision h5 {
	margin-bottom: 12px;
}

#two-columns {
	width: 100%;
	-moz-column-count: 2;
	-moz-column-gap: 64px;
	-webkit-column-count: 2;
	-webkit-column-gap: 64px;
	column-count: 2;
	column-gap: 64px;
}
.guidance-block {
	padding: 24px 0 !Important;
	margin-bottom: 10px;
	display: block !Important;
	overflow: hidden !Important;
	transition-property: box-shadow !Important;
	transition-duration: 0.2s !Important;
	-webkit-box-shadow: inset 0 -1px 0 0 #e3e7e8 !Important;
	box-shadow: inset 0 -1px 0 0 #e3e7e8 !Important;
}
.guidance-block .title {
	color: #0093da !Important;
	font-size: 24px !Important;
	line-height: 24px !Important;
	margin-bottom: 20px !Important;
}
.guidance-block p {
	margin: 0;
	color: #374248;
}

h1, h2, h3, h4, h5, h6 {
	margin: 0 0 24px;
	font-family: inherit;
	font-weight: 600;
	line-height: normal;
	color: #0e0e0e;
	text-rendering: optimizelegibility;
}
h1 {
	font-size: 48px;
      padding-bottom: 11px;
      border-bottom: 1px solid #ddd;
}
h2 {
	font-size: 36px;
}
h3 {
	font-size: 24px;
}
h4 {
	font-size: 18px;
}
hr {
	margin: 0 0 14px;
	border: 0;
	margin: 24px 0;
	border-top: 1px solid #DCDCDC;
	border-bottom: 1px solid #fff;
}
  h1 strong, h2 strong, h3 strong, h4 strong, h5 strong, h6 strong, h1 b, h2 b, h3 b, h4 b, h5 b, h6 b {
    font-weight: inherit;
  }

body.interactionsList h1,
body.aboutIndex h1,
body.bodySystemIndex h1,
body.woundManagementWithMenu h1,
body.guidanceHome h1,
body.medicinalForms h1,
body.drug h1,
body.drugClass h1,
body.borderlineSubstance h1,
body.clinicalMedicalDeviceInformationGroup h1,
body.MedicalDevice h1 {
	border-bottom: 0px;
}

a:focus, button:focus, button.btn.back-to-top:focus, button.btn.back-to-top:hover { outline: 3px solid #0092a6; }

@media (max-width: 900px) {
	.hidden-xs {
	  display: none;
	}
}


.phase-banner-alpha {
	padding: 0px 0 10px 0;
	border-bottom: 1px solid #bfc1c3;
	margin-bottom: 20px;
}
.phase-banner-alpha.pull-right {
	border-bottom: 0px;
	margin-bottom: 0px;
}
.phase-banner-alpha .phase-tag {
	display: -moz-inline-stack;
	display: inline-block;
	vertical-align: top;
	margin: 0 8px 0 0;
	padding: 2px 5px 2px;
	font-size: 16px;
	line-height: 1.1428571429;
	font-weight: 700;
	text-transform: none;
	text-transform: uppercase;
	letter-spacing: 1px;
	text-decoration: none;
	color: #fff;
	/*background-color: #1a9908;*/
	background-color: #A52A2A;
}

.migration-panel {
	padding: 0px 0 10px 0;
    border-bottom: 1px solid #bfc1c3;
    margin: 15px 0 20px 0;
    font-weight: bold;
}

.breadcrumb {
	margin-top: 20px;
	margin-bottom: 10px;
}

.topic-container .breadcrumb {
	margin-top: none;
}

@media (max-width: 814px) {
	.phase-banner-alpha.pull-right {
		margin-top: 16px;
	}
}

@media (max-width: 752px) {
	body.drug .content-primary .monograph-navigation {
		display: none;
	}
	body.drug .content-primary .monograph-navigation.visible {
		display: block;
	}
}
// body.drug .content-primary .nav-toggle {
// 	display: block;
// }
// body.drug .content-primary .nav-toggle.shown {
// 	display: none;
// }
@media (min-width: 753px) {
	body.drug .content-primary .nav-toggle {
		display: none;
	}
}

.btn-transparent {
	background-color: transparent !important;
	text-align: left;
	color: #005ea5 !important;
	padding-bottom: 20px !important;
}

.media .media-body {
	padding: 0px 0px;
}
.hero-unit {
  padding: 12px 24px;
  margin: -24px 0 24px;
	margin-bottom: 0px;
	font-size: 16px;
	font-weight: 400;
	line-height: 24px;
	color: #fff;
	background-color: #374248;
}
/*.btn {
	color: #333;
	background: #BFC1C3;
	outline: 0;
}*/
.btn-large,
.btn-xl {
	font-size: 20px;
	margin-top: 14px;
	padding: 24px 24px;
	text-transform: none;
	text-align: left;
	margin-bottom: 14px;
}
/*.btn:hover,
.btn:focus,
.btn.active,
.btn:active {
	color: #fff;
	background: #005EA5;
}*/
.btn-toolbar {
	font-size: 0 !Important;
	margin-top: 8px !Important;
	margin-bottom: 0px !Important;
}
.restrict-width {
	width: 100%;
	max-width: 1170px;
	margin-left: auto;
	margin-right: auto;
}
#homepage.homepage .about-panel-nav {
	background-color: #264965;
	margin-bottom: -24px
}
#homepage.homepage .about-panel-nav ul li a {
	padding: 26px 20.5px;
}

ul.unstyled, ol.unstyled {
	margin-bottom: 24px;
}


.nav-subtopics {
  /*width: 100%;
  -moz-column-count: 2;
  -moz-column-gap: 64px;
  -webkit-column-count: 2;
  -webkit-column-gap: 64px;
  column-count: 2;
  column-gap: 64px;*/
}
// .nav-subtopics li.active {
// 	background-color: #0093da;
// }
// .nav-subtopics li.active a {
// 	color: white;
// 	font-weight: bold;
// }

.fixed-scroll-nav.fixed {
	position: fixed;
	top: 15px;
	background-color: white;
	z-index: 4;
	max-height: 90%;
	overflow: auto;
	overflow-x: hidden;
	overflow-y: auto;

	border-radius: 0 0 8px 8px;
}
@media (max-width: 1920px) {
    .fixed-scroll-nav.fixed {
        width: 29%;
    }
}

@media (max-width: 1200px) {
    .fixed-scroll-nav.fixed {
        width: 29%;
    }
}

@media (max-width: 962px) {
    .fixed-scroll-nav.fixed {
        top: auto;
        width: auto;
        position: relative;
    }
}



.layout {
  margin-top: 0;
  margin-bottom: 0;
}
.layout-secondary-wide nav {
	margin-bottom: 24px;
}

body>.layout {
	margin-top: 0px;
	margin-bottom: 12px;
}
.bar {
	border-top: 10px solid #03a9f4;
}
.longbar {
	margin-right: auto;
	margin-left: auto;
	margin-bottom: 10px;
}
img {
	max-width: 100%;
	width: auto\9;
	height: auto;
	padding-left: 0px;
	margin-bottom: 10px;
	vertical-align: middle;
	border: 0;
	-ms-interpolation-mode: bicubic;
}
body #nice-global .nice-search {
	float: none;
	width: 100%;
	margin-left: auto;
	margin-right: auto;
	margin-top: 23px;
	margin-bottom: 10px;
	max-width: 1170px;
}
  .publication {
    border-top: 10px solid #03a9f4;
    overflow: hidden;
    text-align: right;
    padding: 24px 0;
  }
  .publication-brand {
    float: left;
    max-width: 100%;
    width: auto\9;
    height: auto;
    padding-left: 24px;
    vertical-align: middle;
    border: 0;
    -ms-interpolation-mode: bicubic;
  }
  
  .nice-global .nice-search {
    width: 100%;
  }
  .nice-global .nice-search input {
    font-size: 24px;
    height: 60px;
  }
  .nice-global .nice-search button {
    height: 60px;
    width: 60px;
  }
  .nice-global .nice-search .icon-search {
    font-size: 30px;
  }

  .search-heading {
		font-size: 1.3em;
		color: #393939;
		margin-bottom: 0;
		border-bottom: 1px solid #ccc;
		padding-bottom: 16px;
  }
  .search-heading strong {
  	color: #0e0e0e;
  }
  .search-list {
  	padding-left: 0;
  }
  .search-list .media {
  	border-top: 1px solid #ccc;
  	margin-top: 16px;
  	padding-top: 16px;
  }
	
	.search-homepage {
		display:none;
	}
  .navbar-publication {
    margin-top: -24px;
  }
  .navbar-publication ul {
    text-align: center;
    margin: 12px 0 24px;
  }
  
ul,
ol {
	padding: 0;
	margin: 0 0 10px 24px;
}

	.more-info p {
		margin: 0;
		color: #0e0e0e;
	}
	
  .interaction-list-specific .interaction-list-inherited {
    display: none;
  }

  .interaction-list .interaction {
		border: 1px solid rgb(121, 121, 121);
		margin-bottom: 16px;
		display: flex;
  }
  .interaction-list .interaction-title,
  .interaction-list .interaction-notes,
	.interaction-list .interaction-body,
  .interaction-message {
    padding: 10px;
	}

	.interaction-title, h1 {
		overflow-wrap: break-word;
		hyphens: auto;
	}

	h1.interaction-heading {
		margin-top: 24px;
	}

	.interaction-message {
		border-top: 1px solid rgb(121, 121, 121);
	}	

	.interaction-message:first-child {
		border-top: none;
	}

	.interaction-messages {
		background-color:rgba(247, 214, 136, 1);
		border-left: 1px solid rgb(121, 121, 121);
	}

	.interaction-list .interaction-message.Severe {
  	background-color:rgba(245, 126, 126, 1);
	}

	.interaction-list dl {
		margin-bottom: 0;
	}

	.interaction-list dt {
		width:auto;
		text-overflow: initial;
	}

  .interactions-no-note {
  	display: none;
  }

  .index.unstyled h2,
  .index.unstyled h3,
  .index.unstyled h4 {
  	margin-top: 16px;
  	margin-left: 16px;
  }
  
  nav .aToZ > li > a {
		margin-right: 2px;
		padding: 12px 15px;
		color: #111;
		border: 1px solid #E4E4E4;
		width: 1em;
		height: 1em;
		margin-top: 2px;
		text-align: center;
  }
  nav .aToZ > .active > a {
    background-color: #0074d9;
    border: 1px solid #0074d9;
  }
.doses {
	padding-left: 0;
	list-style: none;
}
.doses .dose {
	padding-left: 24px;
	padding-left: 1rem;
	margin-bottom: 6px;
	margin-bottom: .6rem;
}
/*.doses .adult {
	border-left: 10px solid #0288d1;
}*/
/*.doses .child {
	border-left: 10px solid #82176F;
}*/
.doses .info {
	border-left: 10px solid #468847;
}
  /*.doses .adult,
  .doses .elderly,
  .doses .childbearing {
    border-left: 10px solid #0288d1;
  }
  .doses .child,
  .doses .neonate {
    border-left: 10px solid #82176F;
  }*/
  /*.doses .info {
    border-left: 10px solid #468847;
  }*/
.lead {
	margin-bottom: 0px;
	font-size: 20px;
	font-weight: 400;
	line-height: 28px;
}
  small.footnote {
    display: block;
  }
  
.alert {
	text-shadow: none;
}
.alert-block {
	padding-top: 35px;
	padding-bottom: 35px;
}
.alert,
.alert h4 {
	color: #4a4a4a;
}
.alert {
	padding: 25px;
	margin-bottom: 24px;
	margin-top: 24px;
	text-shadow: 0 1px 0 rgba(255, 255, 255, .5);
	background-color: #fff;
	border: 5px solid #0288d1;
	-webkit-border-radius: 0;
	-moz-border-radius: 0;
	border-radius: 0;
}
.alertselect {
	padding: 13px;
	margin-bottom: 24px;
	margin-top: 0px;
	text-shadow: 0 1px 0 rgba(255, 255, 255, .5);
	background-color: #fff;
	border: 5px solid #0288d1;
	-webkit-border-radius: 0;
	-moz-border-radius: 0;
	border-radius: 0;
}
.alert-info {
	background-color: #f6fbfd;
	border-color: #d9f2f7;
	font-size: 18px;
}
@media only screen and (max-width: 768px) {
	.grid3 li {
		float: left !important;
	}
	body.aToZ h2 {
		margin-top: 24px;
	}
	ul.inline>li,
	ol.inline>li {
			display: none;
	}
	h5.interactant {
		margin: 0;
	}

}
/* DITA symbols */
.tab-content {
	overflow: auto;
}
  .content-primary h2,
  .content-primary h3 {
    padding-bottom: 11px;
    border-bottom: 1px solid #ddd;
  }
  p {
      margin: 0 0 12px;
  }
.tab-content > .tab-pane {
	display: none;
}
.tab-content > .active {
	display: block;
}
.tab-pane {
	padding: 0px;
}
tm::before {
	font-size: .8em;
	margin-left: -.2em;
	vertical-align: top;
}
tm[tmtype=reg]::before {
	content: "\00ae";
}
tm[tmtype=copy]::before {
	content: "\00a9";
}
tm[tmtype=trade]::before {
	content: "\2122";
}

#wrap {
	height: auto;
	width: auto;
	margin: 0 auto;
}
#top-link {
	display: none;
	position: fixed;
	left: 50%;
	margin-left: 78px;
	bottom: 320px;
	color: #292f33;
	font-weight: 400;
	text-decoration: none;
	border: none;
	background: #c1ccd2;
	padding: 12px 18px;
	box-shadow: inset 0 -1px 0 0 rgba(0, 0, 0, .1);
	opacity: 0.8
}
.nav.nav-pills.aToZ li.disabled {
	display: none;
}
.twitter-typeahead .tt-dataset {
	border: 1px solid silver;
	background-color: white;
	width: 100%;
}

.back-to-top-container {
	display: none;
  background-color: transparent;
}
.back-to-top-container.fixed {
	display: block;
  position: fixed;
  bottom: 30px;
  right: 30px;
  z-index: 5;
  padding: 10px;
}


  .index > li > a {
    display: block;
    border-top: 1px solid #E4E4E4;
    padding: 8px 12px;
  }
  .index > li > a:hover,
  .index > li > a:active,
	.index > li > a:focus,
	.more-info a,
	.more-info a:hover  {
    text-decoration: underline;
  }
  address span {
    display: block;
  }





/*
	Homepage cta-ish panel
*/
.main-row {
  border-top: 1px solid #bfc1c3;
  padding-top: 24px;
  margin-top: 12px;
}
.main-row .main-panel {
  padding: 8px 16px;
}
.main-row .browse-panel {
  padding: 0px 16px;
}
.header-panel {
  padding: 8px 16px 0px 16px;
}
/*.main-row .standout-panel {
	background-color: #2F577A;
	color: #eeeeee;
}*/
/*.main-row .standout-panel h1,
.main-row .standout-panel h2,
.main-row .standout-panel h3 {
	color: #eeeeee;
}
.main-row .standout-panel a {
	color: #eeeeee;
}
.main-row .standout-panel a:hover {
	color: white;
}*/
/*
	Aligns homepage panel headers
*/
.main-row h2 {
	margin-top: 0px;
}
.main-row h3 {
	margin-top: 12px;
}
/*
	Main-menu link containers
*/
.standout-panel .main-menu-link-container {
	padding-left: 24px;
}
.main-menu-link .title {
	position: relative;
	margin-top: 0;
  margin-bottom: 4px;
}
/*.main-menu-link,
.main-menu-link .title {
	color: #0093da;
}
.main-menu-link:hover,
.main-menu-link:hover .title {
	color: #007dba;
}*/
/*.standout-panel .main-menu-link,
.standout-panel .main-menu-link .title {
	color: #eeeeee;
}
.standout-panel .main-menu-link:hover,
.standout-panel .main-menu-link:hover .title {
	color: white;
}*/
.main-menu-link:hover .title {
	text-decoration: underline;
}
.main-menu-link:focus .title {
	outline: 3px solid #0092a6;
	color: #005ea5;
}

.main-menu-link.inverse:focus .title {
	outline: 3px solid #fff;
}
/*.main-menu-link p {
	color: #374248;
}*/
/*.standout-panel .main-menu-link p {
	color: #dddddd;
}*/
.main-menu-link .icon-chevron-right {
	position: absolute;
	left: -24px;
	font-size: 16px;
	line-height: 32px;
	font-weight: normal;
}




/*
	AS YOU TYPE
*/
.index.ayt-filtered li {
  display: none;
}
.index.ayt-filtered li.ayt-filter-found {
  display: list-item;
}

.ayt-row-hidden {
	display: none;
}

.ayt-filtered {
  /*background-color: green;*/
}
.considering {
  text-shadow: 2px 2px 2px rgba(255, 255, 0, 0.75);
}
.considering.nomatches {
  text-shadow: 2px 2px 2px rgba(255, 0, 0, 0.5);
}
.considering.hasmatches {
  text-shadow: 2px 2px 2px rgba(0, 255, 0, 0.5);
}
.ayt-warning {
  color: red;
  cursor: pointer;
}

.sticky-notice {
	position: -webkit-sticky;
	position: sticky;
	top: 0;
	margin-top: 0px;
	margin-bottom: 10px;
	z-index: 1;
}

.extra-margin {
	margin-bottom: 10px;
}

#site-distinction {
	border-bottom: 2px solid white;
}


#site-distinction p {
	padding: 5px;
	margin: 0px;
}

#site-distinction a, #site-distinction p {
	color: black;
	font-weight: bold;
	font-size: 105%;
}

#site-distinction p a {
	text-decoration: underline
}

#site-distinction.bnf {
	background-color: #93da49
}

#site-distinction.bnfc {
	background-color: #ef4b81
}

/* Accessibility overrides */

.h2, .h4, .h5 {
    padding-bottom: 0 !important;
    border-bottom-width: 0 !important;
}

.h2, .h3, .h3-content, .h4 {
	margin: 0 0 24px;
}

.h2 small, .h3 small, .h3-content small, .h4 small, .h5 small {
    font-weight: 400;
    line-height: 1;
}

.h3 small, .h3-content small, .h4 small {
    font-size: 16px;
}

.h2 { 
	font-size: 36px; 
}

.h3, table.table caption {
	font-size: 24px;	
	padding-bottom: 11px !important;
    border-bottom: 1px solid #ddd !important;
}
.h3-content {
	font-weight: 600 !important;
	font-size: 24px !important;	
	padding-bottom: 11px !important;
	border-bottom-width: 0 !important;
}
table.table caption {
	margin: 0 0 24px;
	text-align: left;
    font-family: inherit;
    font-weight: 600;
    line-height: normal;
}

.h4 {
    font-size: 18px;
}

.h5 {
    font-size: 16px;
    margin: 0 0 12px;
}

span.strengthOfActiveIngredient {
	display: block;
}

span.badge.badge-warning {
	color: #0e0e0e;
}